Our mission
For manufacturers and healthcare professionals, EndoVx offers an integrated solution for optimized treatment of aortic aneurysms, combining AI, 3D printing, and digital simulation.
Clinical context
An aortic aneurysm is a permanent, abnormal dilation of the arterial diameter. It can develop in any section of the aorta—thoracic, abdominal, or thoracoabdominal. Among aortic lesions, abdominal aortic aneurysms are the most common, with a global prevalence estimated between 1 and 2% in women and 4 to 8% in men over 65 years.
AAA prevalence
175’000 worlwide
1.2% of women
7.6% of men
in population over 50
AAA prevalence
~ 350’000
grafts / year
worlwide
Existing treatments
Once an aneurysm reaches a critical diameter threshold or ruptures, surgical repair is required. This can be performed:
- Via open surgery; the diseased segment of the aorta is replaced with a synthetic graft.
- Through minimally invasive endovascular techniques (EVAR), involving the placement of a covered stent-graft via an endovascular approach.
Limitations
- EVAR is not suitable for all patients, depending on aneurysm shape or location.
- The procedure is restricted to specialized centers with advanced infrastructure and trained staff.
- Customized stent grafts are costly and time-intensive to produce, and suboptimal design may increase complication risks.
How we do it
The EndoVx project was selected by the French National Research Agency’s (ANR) University Hospital Health Research (RHU) calls for proposals and is funded by the France 2030 investment plan. Led by Marie Lannelongue Hospital (part of the Fondation Hôpital Saint-Joseph) and directed by Professor Stéphan Haulon, the project brings together a consortium of academic, industrial, and hospital partners.
Its ambition is to transform the endovascular treatment of aortic aneurysms through four innovative solutions, each targeting a key stage of the patient care pathway:
- A digital platform for clinicians, integrating artificial intelligence and digital simulation tools for diagnosis, longitudinal follow-up, and the design and simulation of custom endoprostheses.
- A novel material and 3D printing manufacturing process, designed to reduce production time, costs, and complications.
- High-fidelity anatomical models for surgical training and preclinical validation.
- Advanced digital tools to enhance intraoperative guidance in hybrid operating rooms.
A renowned coordinator
Pr. Stéphan Haulon
Professor of Vascular Surgery
Head of Aortic Center
and Vascular Surgery
Meet us
PARIS VASCULAR INSIGHTS COURSE
December 11-13, 2025
Carrousel du Louvre, Paris
PARIS VASCULAR AORTIC COURSE
March 30 – April 4, 2026
Marie-Lannelongue Hospital
Funding & support
EndoVx is laureate of the “University Hospital Health Research” (RHU) call for projects of the France 2030 programme, managed by the French National Research Agency (ANR), which aims to support innovative, large-scale research projects in the healthcare field.
EndoVx project (ANR-21-RHUS-0011) is a national consortium of academic and industrial partners to develop innovative tools for treating aortic lesions. Coordinated by Marie-Lannelongue Hospital, a reference center in aortic surgery, this initiative leverages the complementary expertise of a world-class consortium, where each partner contributes highly specialized know-how.